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human TFR2 shRNA silencing Adenovirus

Name 
Ad-h-TFR2-shRNA
Cat No 
shADV-225373
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human TFR2.

shADV-225373
Ad-h-TFR2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TFR2 (transferrin receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HFE3; TFRC2
Description (Vector)
TFR2 encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
7036
Gene Name (Vector)
transferrin receptor 2
Gene Symbol
TFR2
HGNC ID
HGNC:11762
ORF Size (aa)
2406
ORF Size (bp)
2406 bp
RefSeq ID
NM_003227
RefSeq Synonyms
NM_003227, NM_001206855, BC142630,
Species
human
UniGene ID
Hs.544932

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.