human PPP6C Over-expression AAV

Name 
AAV-h-PPP6C
Cat No 
AAV-219688
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PPP6C.

AAV-219688
AAV-h-PPP6C

Ready-to-use AAV expressing Human PPP6C (protein phosphatase 6 catalytic subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PP6; PP6C; serine/threonine protein phosphatase catalytic subunit; serine/threonine-protein phosphatase 6 catalytic subunit
Description (eCommerce)
PPP6C is the protein phosphatase 6 catalytic subunit that is a member of the large PPP family of serine/threonine protein phosphatases. PPP6C is a type -2A phosphatase and is structurally related to PP2A and PP4. PP6 has been shown to play a role in the cell cycle through its regulation of cyclin D1. PPP6C has also been implicated in the negative control of NF-kappaB and TAK1 activation.
Description (Vector)
PPP6C encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X.
Gene ID
5537
Gene Name (eCommerce)
protein phosphatase 6 catalytic subunit
Gene Name (Vector)
protein phosphatase 6 catalytic subunit
Gene Symbol
PPP6C
HGNC ID
HGNC:9323
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
918
Protein Name (eCommerce)
Serine/threonine-protein phosphatase 6 catalytic subunit
RefSeq ID
NM_002721
RefSeq Synonyms
NM_002721, NM_001123369, NM_001123355, BC006990,
Research Areas
Cell Cycle,Interleukin Signaling,Kinase/Phosphatase,Phosphatase,Signal Transduction,TNF Signaling
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,immunology,signal_transduction
Species
human
Target Sentence
PPP6C is the protein phosphatase 6 catalytic subunit that is a member of the large PPP family of serine/threonine protein phosphatases. PPP6C is a type -2A phosphatase and is structurally related to PP2A and PP4. PP6 has been shown to play a role in the cell cycle through its regulation of cyclin D1. PPP6C has also been implicated in the negative control of NF-kappaB and TAK1 activation.
UniGene ID
Hs.715605
UniProt ID (eCommerce)
O00743

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.