mouse PPP6C shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ppp6c.
shAAV-269260
AAV-m-PPP6C-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ppp6c (protein phosphatase 6, catalytic subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310003C10Rik
Description (Vector)
Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.
Gene ID
67857
Gene Name (Vector)
protein phosphatase 6, catalytic subunit
Gene Symbol
Ppp6c
ORF Size (aa)
918
ORF Size (bp)
918 bp
RefSeq ID
NM_024209
RefSeq Synonyms
NM_024209, BC002223,
Species
mouse
UniGene ID
Mm.392662
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.