human PNPT1 Over-expression AAV

Name 
AAV-h-PNPT1
Cat No 
AAV-219323
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PNPT1.

AAV-219323
AAV-h-PNPT1

Ready-to-use AAV expressing Human PNPT1 (polyribonucleotide nucleotidyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3'-5' RNA exonuclease OLD35; COXPD13; DFNB70; OLD35; old-35; PNPASE; PNPase 1; PNPase old-35; polynucleotide phosphorylase 1; polynucleotide phosphorylase-like protein; polyribonucleotide nucleotidyltransferase 1, mitochondrial
Description (eCommerce)
Polyribonucleotide nucleotidyltransferase 1 (PNPase) is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TCS8].
Description (Vector)
PNPT1 is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation (Raijmakers et al., 2002 (PubMed 12419256)).(supplied by OMIM, Mar 2008)
Gene ID
87178
Gene Name (eCommerce)
polyribonucleotide nucleotidyltransferase 1
Gene Name (Vector)
polyribonucleotide nucleotidyltransferase 1
Gene Symbol
PNPT1
HGNC ID
HGNC:23166
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2352
ORF Size (bp)
2352 bp
Protein Name (eCommerce)
Polyribonucleotide nucleotidyltransferase 1, mitochondrial
RefSeq ID
NM_033109
RefSeq Synonyms
NM_033109, BC053660,
Research Areas
Cell Cycle,IFN Signaling,Mitochondrion,mRNA Processing,Neurobiology,RNA Binding,RNA Processing,Signal Transduction
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,immunology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Polyribonucleotide nucleotidyltransferase 1 (PNPase) is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TCS8].
UniGene ID
Hs.388733
UniProt ID (eCommerce)
Q8TCS8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.