human PNPT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PNPT1.
shAAV-219323
AAV-h-PNPT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PNPT1 (polyribonucleotide nucleotidyltransferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3'-5' RNA exonuclease OLD35; COXPD13; DFNB70; OLD35; old-35; PNPASE; PNPase 1; PNPase old-35; polynucleotide phosphorylase 1; polynucleotide phosphorylase-like protein; polyribonucleotide nucleotidyltransferase 1, mitochondrial
Description (eCommerce)
Polyribonucleotide nucleotidyltransferase 1 (PNPase) is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TCS8].
Description (Vector)
PNPT1 is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation (Raijmakers et al., 2002 (PubMed 12419256)).(supplied by OMIM, Mar 2008)
Gene ID
87178
Gene Name (eCommerce)
polyribonucleotide nucleotidyltransferase 1
Gene Name (Vector)
polyribonucleotide nucleotidyltransferase 1
Gene Symbol
PNPT1
HGNC ID
HGNC:23166
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2352
ORF Size (bp)
2352 bp
Protein Name (eCommerce)
Polyribonucleotide nucleotidyltransferase 1, mitochondrial
RefSeq ID
NM_033109
RefSeq Synonyms
NM_033109, BC053660,
Research Areas
Cell Cycle,IFN Signaling,Mitochondrion,mRNA Processing,Neurobiology,RNA Binding,RNA Processing,Signal Transduction
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,immunology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Polyribonucleotide nucleotidyltransferase 1 (PNPase) is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TCS8].
UniGene ID
Hs.388733
UniProt ID (eCommerce)
Q8TCS8
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.