human PARVA Over-expression AAV

Name 
AAV-h-PARVA
Cat No 
AAV-218251
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PARVA.

AAV-218251
AAV-h-PARVA

Ready-to-use AAV expressing Human PARVA (parvin alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
actopaxin; alpha-parvin; calponin-like integrin-linked kinase-binding protein; CH-ILKBP; matrix-remodeling-associated protein 2; MXRA2
Description (eCommerce)
Actopaxin is a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. Actopaxin is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival [taken from NCBI Entrez Gene (Gene ID: 55742)].
Description (Vector)
PARVA encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival.
Gene ID
55742
Gene Name (eCommerce)
parvin alpha
Gene Name (Vector)
parvin alpha
Gene Symbol
PARVA
HGNC ID
HGNC:14652
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
Protein Name (eCommerce)
Alpha-parvin
RefSeq ID
NM_018222
RefSeq Synonyms
NM_018222, BC016713, BC014535,
Research Areas
Angiogenesis,Cytoskeleton,Signal Transduction
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,signal_transduction
Species
human
Target Sentence
Actopaxin is a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. Actopaxin is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival [taken from NCBI Entrez Gene (Gene ID: 55742)].
UniGene ID
Hs.607144
UniProt ID (eCommerce)
Q9NVD7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.