human PARP2 Over-expression AAV

Name 
AAV-h-PARP2
Cat No 
AAV-218242
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PARP2.

AAV-218242
AAV-h-PARP2

Ready-to-use AAV expressing Human PARP2 (poly(ADP-ribose) polymerase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADPRT2; ADPRTL2; ADPRTL3; ARTD2; pADPRT-2; PARP-2
Description (Vector)
PARP2 encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
Gene ID
10038
Gene Name (Vector)
poly(ADP-ribose) polymerase 2
Gene Symbol
PARP2
HGNC ID
HGNC:272
ORF Size (aa)
1749
ORF Size (bp)
1749 bp
RefSeq ID
NM_005484
RefSeq Synonyms
NM_005484, NM_001042618, BC172288,
Species
human
UniGene ID
Hs.409412

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.