human PARL Over-expression AAV

Name
AAV-h-PARL

Cat No
AAV-218227

Availability
4-5 weeks

This is an AAV expressing Human PARL.

AAV-218227

AAV-h-PARL

Ready-to-use AAV expressing Human PARL (presenilin associated rhomboid like). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PRO2207; PSARL; PSARL1; PSENIP2; RHBDS1

Description (Vector)

PARL encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID

55486

Gene Name (Vector)

presenilin associated rhomboid like

Gene Symbol

PARL

HGNC ID

HGNC:18253

ORF Size (aa)

990

ORF Size (bp)

990 bp

RefSeq ID

NM_018622

RefSeq Synonyms

NM_018622, NM_001324438, NM_001324437, NM_001324436, NM_001037639, BC014058, BC003653,

Species

human

UniGene ID

Hs.478469

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.