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rat SBDS shRNA silencing Adenovirus

Name 
Ad-r-SBDS-shRNA
Cat No 
shADV-293830
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Sbds.

shADV-293830
Ad-r-SBDS-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Sbds (SBDS ribosome assembly guanine nucleotide exchange factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
97
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.
Gene ID
288615
Gene Name (Vector)
SBDS ribosome assembly guanine nucleotide exchange factor
Gene Symbol
Sbds
ORF Size (aa)
753
RefSeq ID
NM_001008289
RefSeq Synonyms
NM_001008289, BC086335,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.