human OPHN1 Over-expression AAV

Name 
AAV-h-OPHN1
Cat No 
AAV-217428
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human OPHN1.

AAV-217428
AAV-h-OPHN1

Ready-to-use AAV expressing Human OPHN1 (oligophrenin 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARHGAP41; MRX60; OPN1
Description (Vector)
OPHN1 encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked mental retardation with cerebellar hypoplasia and distinctive facial dysmorhphism.
Gene ID
4983
Gene Name (Vector)
oligophrenin 1
Gene Symbol
OPHN1
HGNC ID
HGNC:8148
ORF Size (aa)
2409
ORF Size (bp)
2409 bp
RefSeq ID
NM_002547
RefSeq Synonyms
NM_002547, BC140763,
Species
human
UniGene ID
Hs.128824

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.