mouse OPHN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ophn1.
shAAV-267661
AAV-m-OPHN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ophn1 (oligophrenin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C130037N19Rik; Wtgr
Description (Vector)
Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function (By similarity). Critical for the stabilization of AMPA receptors at post-synaptic sites (By similarity). Critical for the regulation of synaptic vesicle endocytosis at pre-synaptic terminals (By similarity).
Gene ID
94190
Gene Name (Vector)
oligophrenin 1
Gene Symbol
Ophn1
ORF Size (aa)
2409
ORF Size (bp)
2409 bp
RefSeq ID
NM_052976
RefSeq Synonyms
NM_052976, NM_001313756, NM_001313755, NM_001313754, BC004845,
Species
mouse
UniGene ID
Mm.254336
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.