human OPHN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human OPHN1.
shAAV-217428
AAV-h-OPHN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human OPHN1 (oligophrenin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARHGAP41; MRX60; OPN1
Description (Vector)
OPHN1 encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked mental retardation with cerebellar hypoplasia and distinctive facial dysmorhphism.
Gene ID
4983
Gene Name (Vector)
oligophrenin 1
Gene Symbol
OPHN1
HGNC ID
HGNC:8148
ORF Size (aa)
2409
ORF Size (bp)
2409 bp
RefSeq ID
NM_002547
RefSeq Synonyms
NM_002547, BC140763,
Species
human
UniGene ID
Hs.128824
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.