mouse ROS1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ros1.
shADV-270793
Ad-m-ROS1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ros1 (Ros1 proto-oncogene). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
c-ros; Ros-1
Description (Vector)
Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
Gene ID
19886
Gene Name (Vector)
Ros1 proto-oncogene
Gene Symbol
Ros1
ORF Size (aa)
7020
ORF Size (bp)
7020 bp
RefSeq ID
NM_011282
RefSeq Synonyms
NM_011282, BC156297,
Species
mouse
UniGene ID
Mm.236163
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.