human ROS1 shRNA silencing Adenovirus

Name 
Ad-h-ROS1-shRNA
Cat No 
shADV-221501
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ROS1.

shADV-221501
Ad-h-ROS1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
c-ros-1; MCF3; ROS
Description (Vector)
This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.
Gene ID
6098
Gene Name (Vector)
ROS proto-oncogene 1, receptor tyrosine kinase
Gene Symbol
ROS1
HGNC ID
HGNC:10261
ORF Size (aa)
7044
ORF Size (bp)
7044 bp
RefSeq ID
NM_002944
RefSeq Synonyms
NM_002944, BC166687,
Species
human
UniGene ID
Hs.1041

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.