mouse NOTCH3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Notch3.
shADV-265946
Ad-m-NOTCH3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Notch3 (notch 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW229011; hpbk; N3
Description (Vector)
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).
Gene ID
18131
Gene Name (Vector)
notch 3
Gene Symbol
Notch3
ORF Size (aa)
6957
ORF Size (bp)
6957 bp
RefSeq ID
NM_008716
RefSeq Synonyms
NM_008716, BC172738,
Species
mouse
UniGene ID
Mm.439741
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.