mouse NOTCH3 Adenovirus

Name 
Ad-m-NOTCH3
Cat No 
ADV-265946
Availability
4-5 weeks

This is an Adenovirus expressing Mouse Notch3.

ADV-265946
Ad-m-NOTCH3

Ready-to-use Adenovirus expressing Mouse Notch3 (notch 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AW229011; hpbk; N3
Description (Vector)
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).
Gene ID
18131
Gene Name (Vector)
notch 3
Gene Symbol
Notch3
ORF Size (aa)
6957
ORF Size (bp)
6957 bp
RefSeq ID
NM_008716
RefSeq Synonyms
NM_008716, BC172738,
Species
mouse
UniGene ID
Mm.439741

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.