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mouse DCX shRNA silencing Adenovirus

Name 
Ad-m-DCX-shRNA
Cat No 
shADV-256886
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Dcx.

shADV-256886
Ad-m-DCX-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dcx (doublecortin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Dbct
Description (Vector)
Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration.
Gene ID
13193
Gene Name (Vector)
doublecortin
Gene Symbol
Dcx
ORF Size (aa)
1098
ORF Size (bp)
1098 bp
RefSeq ID
NM_010025
RefSeq Synonyms
NM_010025, NM_001110224, NM_001110223, NM_001110222, BC062974, BC057010, BC056391,
Species
mouse
UniGene ID
Mm.12871

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.