mouse DCX shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dcx.
shAAV-256886
AAV-m-DCX-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dcx (doublecortin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Dbct
Description (Vector)
Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration.
Gene ID
13193
Gene Name (Vector)
doublecortin
Gene Symbol
Dcx
ORF Size (aa)
1098
ORF Size (bp)
1098 bp
RefSeq ID
NM_010025
RefSeq Synonyms
NM_010025, NM_001110224, NM_001110223, NM_001110222, BC062974, BC057010, BC056391,
Species
mouse
UniGene ID
Mm.12871
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.