mouse CLEC5A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Clec5a.
shADV-255647
Ad-m-CLEC5A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Clec5a (C-type lectin domain family 5, member a). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Clecsf5; Ly100; MDL-1; Mdl1
Description (Vector)
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation (By similarity). Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
Gene ID
23845
Gene Name (Vector)
C-type lectin domain family 5, member a
Gene Symbol
Clec5a
ORF Size (aa)
573
RefSeq ID
NM_021364
RefSeq Synonyms
NM_021364, NM_001038604, BC104365, BC104364,
Species
mouse
UniGene ID
Mm.103765
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.