human ZIC4 shRNA silencing Adenovirus

Name 
Ad-h-ZIC4-shRNA
Cat No 
shADV-228257
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ZIC4.

shADV-228257
Ad-h-ZIC4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ZIC4 (Zic family member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
ZIC4 encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. ZIC4 is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene.
Gene ID
84107
Gene Name (Vector)
Zic family member 4
Gene Symbol
ZIC4
HGNC ID
HGNC:20393
ORF Size (aa)
1005
RefSeq ID
NM_032153
RefSeq Synonyms
NM_032153, NM_001243256, NM_001168379, NM_001168378, BC136339, BC126267,
Species
human
UniGene ID
Hs.415766

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.