human ZIC4 shRNA silencing AAV

Cat. No: shAAV-228257

Availability: 6-8 weeks

Name: AAV-h-ZIC4-shRNA

This is an AAV expressing shRNA for silencing of Human ZIC4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ZIC4
Gene Name: Zic family member 4
Gene ID: 84107
ORF Size: 1005 bp
RefSeq#: NM_032153
Gene Description: ZIC4 encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. ZIC4 is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene.
UniGene ID: Hs.415766
HGNC ID: HGNC:20393