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human SETD7 shRNA silencing Adenovirus

Name 
Ad-h-SETD7-shRNA
Cat No 
shADV-222739
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SETD7.

shADV-222739
Ad-h-SETD7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SETD7 (SET domain containing lysine methyltransferase 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
H3-K4-HMTase SETD7; histone H3-K4 methyltransferase SETD7; histone H3-lysine 4-specific methyltransferase; histone-lysine N-methyltransferase SETD7; KMT7; lysine N-methyltransferase 7; SET domain-containing protein 7; SET7; SET7/9; SET9
Description (eCommerce)
SET7 is a member of the SET (SuVar3-9, enhancer of Zeste, Trithorax) domain-containing protein family. SET7 functions as a histone methyltransferase that specifically monomethylates lysine-4 of histone H3. SET7 has also been observed to monomethylate non-histone proteins such as p53, TAF10, and the estrogen receptor. The methylating activity of SET7 is essential to cell cycle progression and genomic stability.
Gene ID
80854
Gene Name (eCommerce)
SET domain containing lysine methyltransferase 7
Gene Name (Vector)
SET domain containing lysine methyltransferase 7
Gene Symbol
SETD7
HGNC ID
HGNC:30412
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1101
ORF Size (bp)
1101 bp
Protein Name (eCommerce)
Histone-lysine N-methyltransferase SETD7
RefSeq ID
NM_030648
RefSeq Synonyms
NM_030648, NM_001306200, NM_001306199, BC121056, BC121055,
Research Areas
Chromatin Remodeling,Histone Modification,Methyltransferase,Neurobiology,p53 Signaling,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
signal_transduction,cell_biology,transcription_translation,genetics,cell_biology,neurobiology,signal_transduction,genetics,transcription_translation
Species
human
Target Sentence
SET7 is a member of the SET (SuVar3-9, enhancer of Zeste, Trithorax) domain-containing protein family. SET7 functions as a histone methyltransferase that specifically monomethylates lysine-4 of histone H3. SET7 has also been observed to monomethylate non-histone proteins such as p53, TAF10, and the estrogen receptor. The methylating activity of SET7 is essential to cell cycle progression and genomic stability.
UniGene ID
Hs.480792
UniProt ID (eCommerce)
Q8WTS6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.