human SETD7 shRNA silencing AAV

Name
AAV-h-SETD7-shRNA

Cat No
shAAV-222739

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human SETD7.

shAAV-222739

AAV-h-SETD7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SETD7 (SET domain containing lysine methyltransferase 7). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

H3-K4-HMTase SETD7; histone H3-K4 methyltransferase SETD7; histone H3-lysine 4-specific methyltransferase; histone-lysine N-methyltransferase SETD7; KMT7; lysine N-methyltransferase 7; SET domain-containing protein 7; SET7; SET7/9; SET9

Description (eCommerce)

SET7 is a member of the SET (SuVar3-9, enhancer of Zeste, Trithorax) domain-containing protein family. SET7 functions as a histone methyltransferase that specifically monomethylates lysine-4 of histone H3. SET7 has also been observed to monomethylate non-histone proteins such as p53, TAF10, and the estrogen receptor. The methylating activity of SET7 is essential to cell cycle progression and genomic stability.

Gene ID

80854

Gene Name (eCommerce)

SET domain containing lysine methyltransferase 7

Gene Name (Vector)

SET domain containing lysine methyltransferase 7

Gene Symbol

SETD7

HGNC ID

HGNC:30412

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1101

ORF Size (bp)

1101 bp

Protein Name (eCommerce)

Histone-lysine N-methyltransferase SETD7

RefSeq ID

NM_030648

RefSeq Synonyms

NM_030648, NM_001306200, NM_001306199, BC121056, BC121055,

Research Areas

Chromatin Remodeling,Histone Modification,Methyltransferase,Neurobiology,p53 Signaling,Signal Transduction,Transcription Factor/Regulator

Research Areas (Faceted)

signal_transduction,cell_biology,transcription_translation,genetics,cell_biology,neurobiology,signal_transduction,genetics,transcription_translation

Species

human

Target Sentence

SET7 is a member of the SET (SuVar3-9, enhancer of Zeste, Trithorax) domain-containing protein family. SET7 functions as a histone methyltransferase that specifically monomethylates lysine-4 of histone H3. SET7 has also been observed to monomethylate non-histone proteins such as p53, TAF10, and the estrogen receptor. The methylating activity of SET7 is essential to cell cycle progression and genomic stability.

UniGene ID

Hs.480792

UniProt ID (eCommerce)

Q8WTS6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.