mouse SETD7 Adenovirus
This is an Adenovirus expressing Mouse Setd7.
ADV-281082
Ad-m-SETD7
Ready-to-use Adenovirus expressing Mouse Setd7 (SET domain containing (lysine methyltransferase) 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1600028F23Rik; H3K4MT; KMT7; mKIAA1717; Set7; Set7/9
Description (Vector)
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
Gene ID
73251
Gene Name (Vector)
SET domain containing (lysine methyltransferase) 7
Gene Symbol
Setd7
ORF Size (aa)
1101
ORF Size (bp)
1101 bp
RefSeq ID
NM_080793
RefSeq Synonyms
NM_080793, BC050190,
Species
mouse
UniGene ID
Mm.192111
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.