human PROZ shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PROZ.
shADV-219944
Ad-h-PROZ-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PROZ (protein Z, vitamin K dependent plasma glycoprotein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PZ
Description (Vector)
PROZ encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.
Gene ID
8858
Gene Name (Vector)
protein Z, vitamin K dependent plasma glycoprotein
Gene Symbol
PROZ
HGNC ID
HGNC:9460
ORF Size (aa)
1203
ORF Size (bp)
1203 bp
RefSeq ID
NM_003891
RefSeq Synonyms
NM_003891, NM_001256134, BC074907, BC074906,
Species
human
UniGene ID
Hs.1011
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.