human PARD6A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PARD6A.
shADV-218220
Ad-h-PARD6A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PARD6A (par-6 family cell polarity regulator alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PAR-6A; PAR6; PAR6alpha; PAR6C; TAX40; TIP-40
Description (Vector)
PARD6A is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
50855
Gene Name (Vector)
par-6 family cell polarity regulator alpha
Gene Symbol
PARD6A
HGNC ID
HGNC:15943
ORF Size (aa)
1038
ORF Size (bp)
1038 bp
RefSeq ID
NM_016948
RefSeq Synonyms
NM_016948, NM_001037281, BC015626,
Species
human
UniGene ID
Hs.112933
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.