human PARD6A shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-218220
Availability:
4-5 weeks
Name:
AAV-h-PARD6A-shRNA
This is an AAV expressing shRNA for silencing of Human PARD6A.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PARD6A
- Gene Name
- par-6 family cell polarity regulator alpha
- Gene ID
- 50855
- Gene Synonyms
- PAR-6A; PAR6; PAR6alpha; PAR6C; TAX40; TIP-40
- ORF Size
- 1038 bp
- RefSeq#
- NM_016948
- Gene Description
- PARD6A is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- UniGene ID
- Hs.112933
- HGNC ID
- HGNC:15943
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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