human MKL2 shRNA silencing Adenovirus

Name 
Ad-h-MKL2-shRNA
Cat No 
shADV-215500
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human MKL2.

shADV-215500
Ad-h-MKL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MKL2 (MKL1/myocardin like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CTA-276F8.1; megakaryoblastic leukemia 2; MKL and myocardin family member 2; MKL/myocardin like 2; MKL/myocardin-like protein 2; MKL1/myocardin like 2; MKL2; MRTF-B; NPD001
Description (eCommerce)
Megakaryoblastic leukemia 2 (MKL2) is a transcriptional coactivator of serum response factor (SRF). MKL2 is required for skeletal myogenic differentiation.
Gene ID
57496
Gene Name (eCommerce)
myocardin related transcription factor B
Gene Name (Vector)
MKL1/myocardin like 2
Gene Symbol
MKL2
HGNC ID
HGNC:29819
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3300
ORF Size (bp)
3300 bp
Protein Name (eCommerce)
MKL/myocardin-like protein 2
RefSeq ID
NM_014048
RefSeq Synonyms
NM_014048, NM_001308142, BC171750, BC136260, BC047761,
Research Areas
Cell Biology,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Megakaryoblastic leukemia 2 (MKL2) is a transcriptional coactivator of serum response factor (SRF). MKL2 is required for skeletal myogenic differentiation.
UniGene ID
Hs.49143
UniProt ID (eCommerce)
Q9ULH7

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.