human MKL2 Adenovirus
This is an Adenovirus expressing Human MKL2.
ADV-215500
Ad-h-MKL2
Ready-to-use Adenovirus expressing Human MKL2 (MKL1/myocardin like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CTA-276F8.1; megakaryoblastic leukemia 2; MKL and myocardin family member 2; MKL/myocardin like 2; MKL/myocardin-like protein 2; MKL1/myocardin like 2; MKL2; MRTF-B; NPD001
Description (eCommerce)
Megakaryoblastic leukemia 2 (MKL2) is a transcriptional coactivator of serum response factor (SRF). MKL2 is required for skeletal myogenic differentiation.
Gene ID
57496
Gene Name (eCommerce)
myocardin related transcription factor B
Gene Name (Vector)
MKL1/myocardin like 2
Gene Symbol
MKL2
HGNC ID
HGNC:29819
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3300
ORF Size (bp)
3300 bp
Protein Name (eCommerce)
MKL/myocardin-like protein 2
RefSeq ID
NM_014048
RefSeq Synonyms
NM_014048, NM_001308142, BC171750, BC136260, BC047761,
Research Areas
Cell Biology,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Megakaryoblastic leukemia 2 (MKL2) is a transcriptional coactivator of serum response factor (SRF). MKL2 is required for skeletal myogenic differentiation.
UniGene ID
Hs.49143
UniProt ID (eCommerce)
Q9ULH7
Related Citations
- A hypothesis for insulin resistance in primary human adipocytes involving MRTF-A and suppression of PPAR¿. B Hansson, etc, (2020), Biochemical and Biophysical Research Communications
- Nexilin/NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family coactivators and YAP. B Zhu, etc, (2018), Scientific Reports
- Rosiglitazone drives cavin-2/SDPR expression in adipocytes in a CEBPa-dependent manner. Hansson B, etc, (2017), PLoS ONE
- Similar regulatory mechanisms of caveolins and cavins by myocardin family coactivators in arterial and bladder smooth muscle. Zhu B, etc, (2017), PLoS ONE
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.