human MAP4K2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MAP4K2.
shADV-214950
Ad-h-MAP4K2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BL44; GCK; RAB8IP
Description (Vector)
MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Gene ID
5871
Gene Name (Vector)
mitogen-activated protein kinase kinase kinase kinase 2
Gene Symbol
MAP4K2
HGNC ID
HGNC:6864
ORF Size (aa)
2439
ORF Size (bp)
2439 bp
RefSeq ID
NM_004579
RefSeq Synonyms
NM_004579, NM_001307990, BC047865,
Species
human
UniGene ID
Hs.534341
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.