human ARHGEF18 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ARHGEF18.
shADV-214072
Ad-h-ARHGEF18-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ARHGEF18 (Rho/Rac guanine nucleotide exchange factor 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
P114-RhoGEF
Description (Vector)
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
23370
Gene Name (Vector)
Rho/Rac guanine nucleotide exchange factor 18
Gene Symbol
ARHGEF18
HGNC ID
HGNC:17090
ORF Size (aa)
3093
ORF Size (bp)
3093 bp
RefSeq ID
NM_015318
RefSeq Synonyms
NM_015318, NM_001130955, BC077721, BC008016,
Species
human
UniGene ID
Hs.465761
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.