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human TNRC6A Adenovirus

Name 
Ad-h-TNRC6A
Cat No 
ADV-226158
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human TNRC6A.

ADV-226158
Ad-h-TNRC6A

Ready-to-use Adenovirus expressing Human TNRC6A (trinucleotide repeat containing 6A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAG repeat protein 26; CAGH26; CTD-2540M10.1; EDIE; EMSY interactor protein; FAME6; glycine-tryptophan protein of 182 kDa; GW1; GW182; GW182 autoantigen; Protein GW1; TNRC6; trinucleotide repeat-containing gene 6A protein
Description (eCommerce)
GW182 (glycine-tryptophan protein of 182 kDa) is a member of the trinucleotide repeat containing 6 protein family. It functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. GW182 has been found to associate with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibition of GW182 expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing [taken from NCBI GeneID:27327].
Description (Vector)
TNRC6A encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.
Gene ID
27327
Gene Name (eCommerce)
trinucleotide repeat containing 6A
Gene Name (Vector)
trinucleotide repeat containing 6A
Gene Symbol
TNRC6A
HGNC ID
HGNC:11969
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5889
ORF Size (bp)
5889 bp
Protein Name (eCommerce)
Trinucleotide repeat-containing gene 6A protein
RefSeq ID
NM_014494
RefSeq Synonyms
NM_014494, NM_001330520, BC172409, BC068209,
Research Areas
B-cell Receptor Signaling,Cancer,EGFR Signaling,EGFR Signaling in Cancer,Fc Receptor Signaling,FGF Signaling,Gene Expression,Immunology,Innate Immunity,Neurobiology,NGF Signaling,Notch Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,RNA Binding,RNA Processing,SCF-KIT Signaling,Signal Transduction,Translational Control
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,genetics,immunology,neurobiology,signal_transduction,stem_cell_biology,transcription_translation
Species
human
Target Sentence
GW182 (glycine-tryptophan protein of 182 kDa) is a member of the trinucleotide repeat containing 6 protein family. It functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. GW182 has been found to associate with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibition of GW182 expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing [taken from NCBI GeneID:27327].
UniGene ID
Hs.655057
UniProt ID (eCommerce)
Q8NDV7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.