human CYP8B1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CYP8B1.
shADV-206532
Ad-h-CYP8B1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CYP8B1 (cytochrome P450 family 8 subfamily B member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CP8B; CYP12
Description (Vector)
CYP8B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. CYP8B1 is unique among the cytochrome P450 genes in that it is intronless.
Gene ID
1582
Gene Name (Vector)
cytochrome P450 family 8 subfamily B member 1
Gene Symbol
CYP8B1
HGNC ID
HGNC:2653
ORF Size (aa)
1506
ORF Size (bp)
1506 bp
RefSeq ID
NM_004391
RefSeq Synonyms
NM_004391, BC067444, BC067442, BC067441, BC067434,
Species
human
UniGene ID
Hs.447793
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.