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mouse CYSLTR2 shRNA silencing AAV

Name 
AAV-m-CYSLTR2-shRNA
Cat No 
shAAV-256585
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cysltr2.

shAAV-256585
AAV-m-CYSLTR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cysltr2 (cysteinyl leukotriene receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2300001H05Rik; Cltr2; Cyslt2; CYSLT2R
Description (Vector)
Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
Gene ID
70086
Gene Name (Vector)
cysteinyl leukotriene receptor 2
Gene Symbol
Cysltr2
ORF Size (aa)
930
RefSeq ID
NM_133720
RefSeq Synonyms
NM_133720, NM_001162412, BC132418, BC132414,
Species
mouse
UniGene ID
Mm.158324

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.