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human COX7A2L shRNA silencing Adenovirus

Name 
Ad-h-COX7A2L-shRNA
Cat No 
shADV-205855
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human COX7A2L.

shADV-205855
Ad-h-COX7A2L-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human COX7A2L (cytochrome c oxidase subunit 7A2 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
COX7AR; COX7RP; EB1; SIG81
Description (Vector)
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.
Gene ID
9167
Gene Name (Vector)
cytochrome c oxidase subunit 7A2 like
Gene Symbol
COX7A2L
HGNC ID
HGNC:2289
ORF Size (aa)
345
RefSeq ID
NM_004718
RefSeq Synonyms
NM_004718, NM_001319040, NM_001319038, NM_001319037, NM_001319036, BC007095, BC005251,
Species
human
UniGene ID
Hs.339639

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.