human KIAA0652 Over-expression AAV

Name 
AAV-h-KIAA0652
Cat No 
AAV-212935
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ATG13.

AAV-212935
AAV-h-KIAA0652

Ready-to-use AAV expressing Human ATG13 (autophagy related 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ATG13 autophagy related 13 homolog; autophagy-related protein 13; KIAA0652; PARATARG8
Description (eCommerce)
Autophagy-related protein 13 (ATG13) is an autophagy factor required for autophagosome formation and mitophagy. It is a target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, ATG13 plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75143].
Gene ID
9776
Gene Name (eCommerce)
autophagy related 13
Gene Name (Vector)
autophagy related 13
Gene Symbol
ATG13
HGNC ID
HGNC:29091
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1218
ORF Size (bp)
1218 bp
Protein Name (eCommerce)
Autophagy-related protein 13
RefSeq ID
NM_014741
RefSeq Synonyms
NM_014741, NM_001346360, NM_001346359, NM_001346358, NM_001346357, NM_001346356, NM_001346355, NM_001346354, NM_001346353, NM_001346352, NM_001346351, NM_001346350, NM_001346349, NM_001346348, NM_001346346, NM_001346344, NM_001346342, NM_001346340, NM_001346338, NM_001346337, NM_001346336, NM_001346335, NM_001346334, NM_001346333, NM_001346332, NM_001346331, NM_001346330, NM_001346329, NM_001346328, NM_001346327, NM_001346326, NM_001346325, NM_001346324, NM_001346323, NM_001346322, NM_001346321, NM_001346320, NM_001346319, NM_001346318, NM_001346317, NM_001346316, NM_001346315, NM_001346314, NM_001346313, NM_001346312, NM_001346311, NM_001205122, NM_001205121, NM_001205120, NM_001205119, NM_001142673, BC006191, BC002378, BC001331,
Research Areas
Autophagy,mTOR Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
Autophagy-related protein 13 (ATG13) is an autophagy factor required for autophagosome formation and mitophagy. It is a target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, ATG13 plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75143].
UniGene ID
Hs.127403
UniProt ID (eCommerce)
O75143

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.