human BSCL2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human BSCL2.
shADV-202294
Ad-h-BSCL2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human BSCL2 (BSCL2, seipin lipid droplet biogenesis associated). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GNG3LG; HMN5; PELD; SPG17
Description (Vector)
BSCL2 encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).
Gene ID
26580
Gene Name (Vector)
BSCL2, seipin lipid droplet biogenesis associated
Gene Symbol
BSCL2
HGNC ID
HGNC:15832
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
RefSeq ID
NM_032667
RefSeq Synonyms
NM_032667, NM_001130702, NM_001122955, BC093048, BC041640, BC012140, BC009866, BC004911,
Species
human
UniGene ID
Hs.715615
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.