rat LGI1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Lgi1.
shAAV-293248
AAV-r-LGI1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Lgi1 (leucine-rich, glioma inactivated 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Gene ID
252892
Gene Name (Vector)
leucine-rich, glioma inactivated 1
Gene Symbol
Lgi1
ORF Size (aa)
1674
ORF Size (bp)
1674 bp
RefSeq ID
NM_145769
RefSeq Synonyms
NM_145769, BC089222,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.