human LGI1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human LGI1.
shADV-213868
Ad-h-LGI1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human LGI1 (leucine rich glioma inactivated 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADLTE; ADPAEF; ADPEAF; EPITEMPIN; EPT; ETL1; IB1099
Description (Vector)
LGI1 is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. LGI1 is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.
Gene ID
9211
Gene Name (Vector)
leucine rich glioma inactivated 1
Gene Symbol
LGI1
HGNC ID
HGNC:6572
ORF Size (aa)
1674
ORF Size (bp)
1674 bp
RefSeq ID
NM_005097
RefSeq Synonyms
NM_005097, NM_001308276, NM_001308275, BC022500,
Species
human
UniGene ID
Hs.533670
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.