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rat LGI1 shRNA silencing Adenovirus

Name 
Ad-r-LGI1-shRNA
Cat No 
shADV-293248
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Lgi1.

shADV-293248
Ad-r-LGI1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Lgi1 (leucine-rich, glioma inactivated 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Gene ID
252892
Gene Name (Vector)
leucine-rich, glioma inactivated 1
Gene Symbol
Lgi1
ORF Size (aa)
1674
ORF Size (bp)
1674 bp
RefSeq ID
NM_145769
RefSeq Synonyms
NM_145769, BC089222,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.