human IL18RAP Over-expression AAV

Name 
AAV-h-IL18RAP
Cat No 
AAV-212081
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IL18RAP.

AAV-212081
AAV-h-IL18RAP

Ready-to-use AAV expressing Human IL18RAP (interleukin 18 receptor accessory protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACPL; CD218b; CDw218b; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RB
Description (Vector)
IL18RAP is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
Gene ID
8807
Gene Name (Vector)
interleukin 18 receptor accessory protein
Gene Symbol
IL18RAP
HGNC ID
HGNC:5989
ORF Size (aa)
1374
ORF Size (bp)
1374 bp
RefSeq ID
NM_003853
RefSeq Synonyms
NM_003853, BC137475, BC137474, BC106765, BC106764, BC069630,
Species
human
UniGene ID
Hs.158315

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.