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human IL18RAP shRNA silencing AAV

Name 
AAV-h-IL18RAP-shRNA
Cat No 
shAAV-212081
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IL18RAP.

shAAV-212081
AAV-h-IL18RAP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IL18RAP (interleukin 18 receptor accessory protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACPL; CD218b; CDw218b; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RB
Description (Vector)
IL18RAP is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
Gene ID
8807
Gene Name (Vector)
interleukin 18 receptor accessory protein
Gene Symbol
IL18RAP
HGNC ID
HGNC:5989
ORF Size (aa)
1374
ORF Size (bp)
1374 bp
RefSeq ID
NM_003853
RefSeq Synonyms
NM_003853, BC137475, BC137474, BC106765, BC106764, BC069630,
Species
human
UniGene ID
Hs.158315

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.