human HPRT1 Over-expression AAV

Name 
AAV-h-HPRT1
Cat No 
AAV-211501
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HPRT1.

AAV-211501
AAV-h-HPRT1

Ready-to-use AAV expressing Human HPRT1 (hypoxanthine phosphoribosyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HGPRT; HGPRTase; HPRT; hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 1; testicular tissue protein Li 89
Description (eCommerce)
HPRT1 is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway [taken from NCBI Entrez Gene (Gene ID: 3251)].
Description (Vector)
HPRT1 is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.
Gene ID
3251
Gene Name (eCommerce)
hypoxanthine phosphoribosyltransferase 1
Gene Name (Vector)
hypoxanthine phosphoribosyltransferase 1
Gene Symbol
HPRT1
HGNC ID
HGNC:5157
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
657
Protein Name (eCommerce)
Hypoxanthine-guanine phosphoribosyltransferase
RefSeq ID
NM_000194
RefSeq Synonyms
NM_000194, BC000578,
Research Areas
Immunology,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,Spermatogenesis
Research Areas (Faceted)
cell_biology,developmental_biology,immunology,metabolism,neurobiology
Species
human
Target Sentence
HPRT1 is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway [taken from NCBI Entrez Gene (Gene ID: 3251)].
UniGene ID
Hs.412707
UniProt ID (eCommerce)
P00492

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.