mouse RGS20 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rgs20.
shAAV-270489
AAV-m-RGS20-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rgs20 (regulator of G-protein signaling 20). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2900073E09Rik; Rgsz1
Description (Vector)
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).
Gene ID
58175
Gene Name (Vector)
regulator of G-protein signaling 20
Gene Symbol
Rgs20
ORF Size (aa)
720
ORF Size (bp)
720 bp
RefSeq ID
NM_021374
RefSeq Synonyms
NM_021374, NM_001290372, NM_001177795, BC116929, BC116925,
Species
mouse
UniGene ID
Mm.103771
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.