mouse POLR1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Polr1b.
shAAV-269027
AAV-m-POLR1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Polr1b (polymerase (RNA) I polypeptide B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
128kDa; D630020H17Rik; RPA116; RPA135; RPA2; Rpo1-2
Description (Vector)
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).
Gene ID
20017
Gene Name (Vector)
polymerase (RNA) I polypeptide B
Gene Symbol
Polr1b
ORF Size (aa)
3408
ORF Size (bp)
3408 bp
RefSeq ID
NM_009086
RefSeq Synonyms
NM_009086, BC060656,
Species
mouse
UniGene ID
Mm.259078
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.