human POLR1B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human POLR1B.
shADV-219379
Ad-h-POLR1B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human POLR1B (RNA polymerase I subunit B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RPA135; RPA2; Rpo1-2
Description (Vector)
Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 (PubMed 8921381)).(supplied by OMIM, Mar 2008)
Gene ID
84172
Gene Name (Vector)
RNA polymerase I subunit B
Gene Symbol
POLR1B
HGNC ID
HGNC:20454
ORF Size (aa)
2859
ORF Size (bp)
2859 bp
RefSeq ID
NM_019014
RefSeq Synonyms
NM_019014, NM_001282779, NM_001282777, NM_001282776, NM_001282774, NM_001282772, NM_001137604, BC110833,
Species
human
UniGene ID
Hs.86337
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.