mouse PIP4K2A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pip4k2a.
shAAV-268679
AAV-m-PIP4K2A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pip4k2a (phosphatidylinositol-5-phosphate 4-kinase, type II, alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW742916; Pip5k2a
Description (Vector)
Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size.
Gene ID
18718
Gene Name (Vector)
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Gene Symbol
Pip4k2a
ORF Size (aa)
1218
ORF Size (bp)
1218 bp
RefSeq ID
NM_008845
RefSeq Synonyms
NM_008845, BC011097,
Species
mouse
UniGene ID
Mm.313977
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.