human PIP4K2A shRNA silencing AAV

Name
AAV-h-PIP4K2A-shRNA

Cat No
shAAV-218980

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PIP4K2A.

shAAV-218980

AAV-h-PIP4K2A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PI5P4KA; PIP5K2A; PIP5KII-alpha; PIP5KIIA; PIPK

Description (Vector)

Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family.

Gene ID

5305

Gene Name (Vector)

phosphatidylinositol-5-phosphate 4-kinase type 2 alpha

Gene Symbol

PIP4K2A

HGNC ID

HGNC:8997

ORF Size (aa)

1221

ORF Size (bp)

1221 bp

RefSeq ID

NM_005028

RefSeq Synonyms

NM_005028, NM_001330062, BC018034,

Species

human

UniGene ID

Hs.57079

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.