human GRK6 Over-expression AAV

Name 
AAV-h-GRK6
Cat No 
AAV-210541
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GRK6.

AAV-210541
AAV-h-GRK6

Ready-to-use AAV expressing Human GRK6 (G protein-coupled receptor kinase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
G protein-coupled receptor kinase 6; G protein-coupled receptor kinase GRK6; GPRK6
Description (eCommerce)
G protein-coupled receptor kinase 6 (GRK6) is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation [taken from NCBI Entrez Gene (Gene ID: 2870)].
Description (Vector)
GRK6 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene.
Gene ID
2870
Gene Name (eCommerce)
G protein-coupled receptor kinase 6
Gene Name (Vector)
G protein-coupled receptor kinase 6
Gene Symbol
GRK6
HGNC ID
HGNC:4545
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1770
ORF Size (bp)
1770 bp
Protein Name (eCommerce)
G protein-coupled receptor kinase 6
RefSeq ID
NM_002082
RefSeq Synonyms
NM_002082, NM_001004106, NM_001004105, BC017272, BC009277,
Research Areas
Cardiology,Cardiovascular,EPO Signaling,Interleukin Signaling,JAK-STAT Signaling,Kinase/Phosphatase,Neurobiology,Signal Transduction,VEGF Signaling,Wnt Signaling
Research Areas (Faceted)
cardiovascular,cell_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
G protein-coupled receptor kinase 6 (GRK6) is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation [taken from NCBI Entrez Gene (Gene ID: 2870)].
UniGene ID
Hs.235116
UniProt ID (eCommerce)
P43250

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.