human GNMT Over-expression AAV

Name 
AAV-h-GNMT
Cat No 
AAV-210131
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GNMT.

AAV-210131
AAV-h-GNMT

Ready-to-use AAV expressing Human GNMT (glycine N-methyltransferase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HEL-S-182mP
Description (Vector)
GNMT is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).
Gene ID
27232
Gene Name (Vector)
glycine N-methyltransferase
Gene Symbol
GNMT
HGNC ID
HGNC:4415
ORF Size (aa)
888
ORF Size (bp)
888 bp
RefSeq ID
NM_018960
RefSeq Synonyms
NM_018960, NM_001318865, BC032627,
Species
human
UniGene ID
Hs.144914

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.